For over ten years, between 1983 and 1993, the researchers of medicinal plants, made an extensive experimental research, chemistry, pharmacology and clinical properties of guava leaves, and showed that extracts of Psidium guajava leaves have a group of novel compounds, present only in this plant, known scientifically as gammapironas, belonging to the subclass of flavonoids glycosylated.
Such a set of natural compounds present in the leaves of this tree produced in the body four complementary effects very useful for the treatment of various gastrointestinal disorders, which explains its long and ancient usage to combat diarrhea, cramps and various gastrointestinal complaints:
a) antispasmodic effect due to the antagonistic action of Ca + in the contraction of intestinal and uterine muscle fiber, which explains its usefulness in eliminating diarrhea, intestinal colic and menstrual cramps in a few minutes.
b) intestinal anti-inflammatory effect through its action on the prostaglandin cascade, which explains its usefulness in reducing gastrointestinal inflammation in acute and chronic colitis.
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